Dupuytren's contracture

Understanding the condition

Dupuytren's disease (also called Dupuytren's contracture) is a progressive fibroproliferative disorder affecting the palmar fascia - the connective tissue layer beneath your palm's skin. The condition typically emerges in middle age or later, with greater prevalence in men than women.

The disease manifests as firm thickened areas (nodules) within the palm's fascial bands. These nodules may progress to form cord-like structures that gradually pull one or more fingers toward the palm, limiting extension. Skin dimpling or pitting often accompanies the nodules and cords. Some patients also develop thickened areas over the knuckles (Garrod's pads) or similar changes on their foot soles (plantar fibromatosis).